Overcoming sequence misalignments with weighted structural superposition
نویسندگان
چکیده
منابع مشابه
Overcoming sequence misalignments with weighted structural superposition.
An appropriate structural superposition identifies similarities and differences between homologous proteins that are not evident from sequence alignments alone. We have coupled our Gaussian-weighted RMSD (wRMSD) tool with a sequence aligner and seed extension (SE) algorithm to create a robust technique for overlaying structures and aligning sequences of homologous proteins (HwRMSD). HwRMSD over...
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ژورنال
عنوان ژورنال: Proteins: Structure, Function, and Bioinformatics
سال: 2012
ISSN: 0887-3585
DOI: 10.1002/prot.24134